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BPIQ-I

CAT: 0804-HY-112405Size: 500 µgDry Ice: NoHazardous: No
CAT#:0804-HY-112405Size:500 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BPIQ-I (PD 159121) is a potent and ATP-competitive EGFR tyrosine kinase inhibitor.. BPIQ-I shows anti-proliferative actively[1][2].
CAS Number
[174709-30-9]
Product Name Alternative
PD 159121
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bpiq-i.html
Solubility
10 mM in DMSO
Smiles
CN1C=NC2=CC3=C(NC4=CC=CC(Br)=C4)N=CN=C3C=C21
Molecular Formula
C16H12BrN5
Molecular Weight
354.20
References & Citations
[1]Rae JM, et al. Evaluation of novel epidermal growth factor receptor tyrosine kinase inhibitors. Breast Cancer Res Treat. 2004 Jan;83 (2) :99-107.|[2]Zhou Y, et al. Role of a tyrosine kinase in the CO2-induced stimulation of HCO3- reabsorption by rabbit S2 proximal tubules. Am J Physiol Renal Physiol. 2006 Aug;291 (2) :F358-67.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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