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AS2863619 free base

CAT: 0013-GTR19207323-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19207323-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AS2863619 free base is a potent, orally bioavailable inhibitor of CDK8 and CDK19 that promotes the differentiation of antigen-specific T cells into Foxp3+ regulatory T cells. This conversion is mediated through enhanced STAT5 activation and subsequent Foxp3 gene induction, making it a valuable tool for studying immune tolerance in both in vitro and in vivo models.
CAS Number
2241300-50-3
Field of Research
Cell Biology, Signal Transduction, Stem Cell & Developmental Biology
Smiles
Cc1nc2ccc (cc2[nH]1) -n1c (nc2cnccc12) -c1nonc1N
Molecular Formula
C16H12N8O
Molecular Weight
332.32
Storage Conditions
-20°C
Notes
For research use only.

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