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CSN5i-3

CAT: 0013-GTR19206142-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206142-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CSN5i-3 is a potent, selective, and orally bioavailable small molecule inhibitor of the CSN5 subunit, exhibiting an IC50 of 5.8 nM for CSN-mediated Cul1 deneddylation. Its anticancer activity, demonstrated through in vitro cytotoxicity against various cancer cell lines, makes it a valuable chemical probe for studying CSN complex biology and oncology research.
CAS Number
2375740-98-8
Product Name Alternative
Apoptosis, CSN5i 3, CSN5i3, CSN-5i-3, CSN5i-3
Field of Research
Cell Biology
Purity
98.01% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (9.89 mM) ; DMSO:247.5 mg/mL (489.56 mM)
Smiles
CC (C) n1nc (cc1C (=O) Nc1ccc ([C@H]2[C@@H] (O) CCCc3cncn23) c (c1) -c1ccccc1) C (F) F
Molecular Formula
C28H29F2N5O2
Molecular Weight
505.56
Storage Conditions
-20°C
Notes
For research use only.

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