Products for Research Use Only

CSN5-IN-1

CAT: 0013-GTR19237509-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19237509-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CSN5-IN-1 (Ac-11) is a CSN5 inhibitor with IC50 values of 12.56 μM (FP assay) and 19 μM (fluorescence assay) . It modulates cellular protein levels, reducing PD-L1 and increasing NEDD8-Cul1, making it a useful probe for studying COP9 signalosome function in cancer immunology and protein neddylation pathways.
Field of Research
Cell Biology, Immunology & Inflammation, Neuroscience, Protein Biochemistry
Molecular Formula
C17H22N2O2S
Molecular Weight
318.43
Storage Conditions
-20°C
Notes
For research use only.