Products for Research Use Only

CSN5-IN-2

CAT: 0013-GTR19258590-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258590-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. It increases Cullin 1 neddylation levels in cancer cells and downregulates the expression of RAD51 and PD-L1. CSN5-IN-2 exhibits antitumor activity, which is enhanced when used in combination with Talazoparib.
Field of Research
Cell Biology, Immunology & Inflammation, Molecular Biology, Neuroscience
Storage Conditions
-20°C
Notes
For research use only.