EGFR-IN-1

CAT: 0013-GTR19205971-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19205971-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

EGFR-IN-1 is a potent, orally bioavailable, and irreversible EGFR inhibitor with high selectivity for L858R/T790M mutant forms, including those resistant to gefitinib. It demonstrates robust antiproliferative effects in vitro, such as in H1975 and HCC827 cell lines, and has shown antitumor efficacy in relevant in vivo xenograft models.

CAS Number

1625677-63-5

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

O=C1N (C=2C (=CN=C (NC3=C (OC) C=C (OCCN (C) C) C=C3) N2) C (C) =C1) C4=CC (NC (C=C) =O) =CC=C4

Molecular Formula

C28H30N6O4

Molecular Weight

514.58

Storage Conditions

-20°C

Notes

For research use only.

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sc-80543	EGFR (EGFR.1)
T11157-01	EGFR-IN-1
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HY-19617A-01	EGFR-IN-1 (hydrochloride)
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EGFR-IN-1

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