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JAK-IN-1

CAT: 0013-GTR19206501-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19206501-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK-IN-1 is a potent, cell-permeable inhibitor of JAK kinases, demonstrating a favorable selectivity profile with IC50 values of 0.26 nM (JAK1), 0.8 nM (JAK2), and 3.2 nM (JAK3) . It is a valuable chemical tool for investigating JAK-STAT signaling in cellular and biochemical assays relevant to immunology and oncology research.
CAS Number
1334673-53-8
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
CC (C) (C) [C@@H] (NC (=O) c1c[nH]c2ncc (nc12) C1CC1) C (=O) N1CC (C1) C#N
Molecular Formula
C20H24N6O2
Molecular Weight
380.44
Storage Conditions
-20°C
Notes
For research use only.

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