JAK-IN-14

CAT: 0013-GTR19184301-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19184301-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

JAK-IN-14 (compound 16) is a potent and selective JAK1 inhibitor (IC50 <5 μM) with over 8-fold selectivity against JAK2/JAK3. It functions by binding the JAK1 active site to inhibit its phosphorylation. This inhibitor is a valuable research tool for studying immune, inflammatory, and oncological pathways in both cellular and animal models.

CAS Number

1973485-06-1

Product Name Alternative

JAK IN 14, JAK-IN-14, JAKIN14

Field of Research

Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.27% (May vary between batches)

Solubility

DMSO:5 mg/mL (14.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.99 mM)

Smiles

N#CCC=1C=CC (=C (F) C1) C2=CC=CC3=NC (=CN32) NC (=O) C4CC4

Molecular Formula

C19H15FN4O

Molecular Weight

334.35

Storage Conditions

-20°C

Notes

For research use only.

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