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MYCMI-6

CAT: 0804-HY-124675-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-124675-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MYCMI-6 (NSC354961) is a potent and selective endogenous MYC:MAX protein interactions inhibitor. MYCMI-6 blocks MYC-driven transcription and binds selectively to the MYC bHLHZip domain with a Kd of 1.6 μM. MYCMI-6 inhibits tumor cell growth in a MYC-dependent manner (IC50apoptosis[1].
CAS Number
681282-09-7
Product Name Alternative
NSC354961
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; c-Myc
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mycmi-6.html
Purity
98.14
Solubility
DMSO : 2.4 mg/mL (ultrasonic)
Smiles
NC1=NC(N)=CC=C1/N=N/C2=CC3=NC4=CC=C(OCC)C=C4C(N)=C3C=C2
Molecular Formula
C20H19N7O
Molecular Weight
373.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Castell A, et al. A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation. Sci Rep. 2018 Jul 3;8 (1) :10064.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

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FM170338-01MYCMI-6
A22700-500MYCMI-6 500mg
A22700-100MYCMI-6 100mg
A22700-200MYCMI-6 200mg
A22700-10MYCMI-6 10mg
A22700-5MYCMI-6 5mg
A22700-1MYCMI-6 1mg
A22700-50MYCMI-6 50mg

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