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ML224

CAT: 0013-GTR19204435-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19204435-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML224 (NCGC00242364) is a small molecule antagonist of the thyroid-stimulating hormone receptor (TSHR) . It is a research tool for investigating Graves' disease pathologies, including hyperthyroidism and orbitopathy, with demonstrated activity in both in vitro assays and in vivo animal models.
CAS Number
1338824-21-7
Product Name Alternative
ANTAG 3, ANTAG3, ANTAG-3, ML224, ML-224, ML 224, NCGC 00242364, NCGC00242364, NCGC-00242364, thyrotropin receptor (TSHR), TSH Receptor, TSHReceptor
Field of Research
Pharmacology & Drug Discovery
Purity
99.14% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.28 mM) ; DMSO:80 mg/mL (152.21 mM)
Smiles
COc1ccc (cc1COc1c (C) cc (NC (C) =O) cc1C) C1Nc2ccccc2C (=O) N1Cc1ccco1
Molecular Formula
C31H31N3O5
Molecular Weight
525.59
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
C04464ML224
A21633-25ML224 25mg
A21633-100ML224 100mg
A21633-50ML224 50mg
A21633-10ML224 10mg
A21633-5ML224 5mg
A21633-1ML224 1mg
MBS130656-01ML224(NCGC00242364; ANTAG3)
A21633-10mM-DML224 10mM * 1mL in DMSO

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