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ML221

CAT: 0013-GTR19170261-01Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19170261-01Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML221 is a potent functional antagonist of the apelin/APJ system, inhibiting apelin-13-induced signaling with IC50 values of 0.70 μM (cAMP) and 1.75 μM (β-arrestin) . This compound is a valuable research tool for investigating the APJ receptor's role in cardiovascular function and metabolic diseases in both cellular and animal models.
CAS Number
877636-42-5
Product Name Alternative
ML221, ML-221, ML 221, inhibit, Inhibitor, APJ, Apelin receptor, Apelinreceptor
Field of Research
Pharmacology & Drug Discovery
Purity
97.74% (May vary between batches)
Solubility
DMSO:6.25 mg/mL (16.22 mM)
Smiles
[O-][N+] (=O) c1ccc (cc1) C (=O) Oc1coc (CSc2ncccn2) cc1=O
Molecular Formula
C17H11N3O6S
Molecular Weight
385.35
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

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T4390-01ML221
A19446-10ML221 10mg
A19446-5ML221 5mg
A19446-50ML221 50mg
A19446-100ML221 100mg
A19446-25ML221 25mg
A19446-10mM-DML221 10mM * 1mL in DMSO

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