Products for Research Use Only

CU-76

CAT: 0013-GTR19189998Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19189998Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CU-76 is a selective cGAS inhibitor (IC50 = 0.24 μM) that suppresses DNA-induced IFN-β production in THP-1 cells without affecting the RIG-I/MAVS pathway. This compound is a valuable research tool for studying the cGAS-STING signaling axis in autoimmune disorders, viral infections, and cancer-related inflammation in cellular models.
CAS Number
2400954-58-5
Field of Research
Immunology & Inflammation
Smiles
N (C=1N=C (C (OC) =O) N=C (N) N1) C2=CC (F) =C (I) C (F) =C2
Molecular Formula
C11H8F2IN5O2
Molecular Weight
407.11
Storage Conditions
-20°C
Notes
For research use only.

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