Products for Research Use Only
RegisterLogin

DMT-2'Fluoro-DG (IB) Amidite

CAT: 0013-GTR19189640-01Size: 200 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19189640-01Size:200 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DMT-2'Fluoro-DG (IB) Amidite (2'-F-ibu-dG Phosphoramidite) is a modified nucleoside building block for oligonucleotide synthesis. It is specifically used to incorporate 2'-fluoro-2'-deoxyguanosine analogs into nucleic acid strands for in vitro and in vivo research, including studies on RNAi therapeutics and aptamer stability.
CAS Number
144089-97-4
Field of Research
Cell Biology, Molecular Biology, Musculoskeletal & Connective Tissue Research
Smiles
C (OC[C@@H]1[C@@H] (OP (N (C (C) C) C (C) C) OCCC#N) [C@@H] (F) [C@@H] (O1) N2C3=C (N=C2) C (=O) N=C (NC (C (C) C) =O) N3) (C4=CC=C (OC) C=C4) (C5=CC=C (OC) C=C5) C6=CC=CC=C6
Molecular Formula
C44H53FN7O8P
Molecular Weight
857.91
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Guanosine, 5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)-, 3'-(2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite)
CAS Number144089-97-4
PubChem CID135448972
IUPAC NameN-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-3-fluorooxolan-2-yl]-6-oxo-1H-purin-2-yl]-2-methylpropanamide
Molecular FormulaC44H53FN7O8P
Molecular Weight857.9
XLogP6.1
Topological Polar Surface Area171
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count13
Rotatable Bond Count19
Heavy Atom Count61
Formal Charge0
Complexity1480
SMILES
CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)OP(N(C(C)C)C(C)C)OCCC#N)F
InChI
InChI=1S/C44H53FN7O8P/c1-27(2)40(53)49-43-48-39-37(41(54)50-43)47-26-51(39)42-36(45)38(60-61(58-24-12-23-46)52(28(3)4)29(5)6)35(59-42)25-57-44(30-13-10-9-11-14-30,31-15-19-33(55-7)20-16-31)32-17-21-34(56-8)22-18-32/h9-11,13-22,26-29,35-36,38,42H,12,24-25H2,1-8H3,(H2,48,49,50,53,54)/t35-,36-,38-,42-,61?/m1/s1
InChIKey
KJFUMXZZVYMQEU-AOCJBPQJSA-N
Chemical Structure
2D Structure
2D structure of Guanosine, 5'-O-(bis(4-methoxyphenyl)phenylmethyl)-2'-deoxy-2'-fluoro-N-(2-methyl-1-oxopropyl)-, 3'-(2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite)
CAS: 144089-97-4
CID: 135448972
Formula: C44H53FN7O8P
MW: 857.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight857.9
XLogP36.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count13
Rotatable Bond Count19
Exact Mass857.36772683
Monoisotopic Mass857.36772683
Topological Polar Surface Area171 Ų
Heavy Atom Count61
Formal Charge0
Complexity1480
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19171006DMT-dG (ib) Phosphoramidite
GTR19191171Dmt-2'fluoro-da (bz) amidite
GTR19338781-01DMT-BH2 amidite
GTR19338782-01DMT-BH1 amidite
GTR19191167-01DMT-dG (dmf) Phosphoramidite
GTR19189568-01Dmt-2'-f-dc (ac) amidite
GTR19244077-01Dmt-2fluoro-da (bz) amidite
GTR19222159-015'-O-DMT-N2-DMF-dG
GTR19188845-015'-O-DMT-N2-ibu-dG
GTR19170678-01DMT-2′Fluoro-dU Phosphoramidite

Alternative Products

CatalogName
T38921-01DMT-2'Fluoro-DG (IB) Amidite
MBS5799489DMT-2'Fluoro-DG(IB) Amidite
OR1029734-01Dmt-Dg (Dmf) Amidite
T36756DMT-dG (ib) Phosphoramidite
MBS3616660-01DMT-dG(ib) Phosphoramidite
MBS5797820Dmt-2'fluoro-da(bz) amidite
BUP18712Dmt-2'fluoro-da (bz) amidite
HY-W008848S1DMT-dG (ib) Phosphoramidite-15N5
HY-W008848ADMT-L-dG (ib) Phosphoramidite
HY-W008848S-01DMT-dG (ib) Phosphoramidite-13C10,15N5

Popular Products