DMT-dG(ib) Phosphoramidite-15N5

DMT-dG(ib) Phosphoramidite-15N5

• UNSPSC Description: DMT-dG(ib) Phosphoramidite-15N5 is the 15N labeled DMT-dG(ib) Phosphoramidite[1]. DMT-dG(ib) Phosphoramidite is typically used in the synthesis of DNA[2].
• Target Antigen: DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog
• Type: Isotope-Labeled Compounds
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/dmt-dg-ib-phosphoramidite-15n5.html
• Solubility: 10 mM in DMSO
• Smiles: CC(N(P(OC1C[C@@H](O[C@@H]1COC(C2=CC=C(C=C2)OC)(C3=CC=CC=C3)C4=CC=C(C=C4)OC)[15N]5C([15N]=C([15NH]6)[15NH]C(C(C)C)=O)=C([15N]=CC5)C6=O)OCCC#N)C(C)C)C
• Molecular Weight: 858.91
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported