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ZDLD13

CAT: 0013-GTR19187777-03Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19187777-03Size:100 mg
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Description
ZDLD13 is a potent, orally active, and selective CDK4/CycD3 inhibitor (IC50 = 0.38 μM) with anti-tumor activity against HCT116 colorectal cancer cells. It inhibits proliferation, invasion, and colony formation while inducing apoptosis and G1 cell cycle arrest. This compound has also demonstrated significant efficacy in inhibiting tumor growth in HCT116 xenograft models.
CAS Number
2762278-95-3
Field of Research
Cell Biology
Smiles
C (NCC1=CC=CC=N1) (=O) C2=C3C (C=4C (N3) =CC=CC4) =CC=N2
Molecular Formula
C18H14N4O
Molecular Weight
302.33
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

N-(pyridin-2-ylmethyl)-9H-pyrido[3,4-b]indole-1-carboxamide
CAS Number2762278-95-3
PubChem CID163321906
IUPAC NameN-(pyridin-2-ylmethyl)-9H-pyrido[3,4-b]indole-1-carboxamide
Molecular FormulaC18H14N4O
Molecular Weight302.3
XLogP2.4
Topological Polar Surface Area70.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Heavy Atom Count23
Formal Charge0
Complexity429
SMILES
C1=CC=C2C(=C1)C3=C(N2)C(=NC=C3)C(=O)NCC4=CC=CC=N4
InChI
InChI=1S/C18H14N4O/c23-18(21-11-12-5-3-4-9-19-12)17-16-14(8-10-20-17)13-6-1-2-7-15(13)22-16/h1-10,22H,11H2,(H,21,23)
InChIKey
BEKOCIRJTAEVEV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-(pyridin-2-ylmethyl)-9H-pyrido[3,4-b]indole-1-carboxamide
CAS: 2762278-95-3
CID: 163321906
Formula: C18H14N4O
MW: 302.3
Interactive 3D Structure
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View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight302.3
XLogP32.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass302.11676108
Monoisotopic Mass302.11676108
Topological Polar Surface Area70.7 Ų
Heavy Atom Count23
Formal Charge0
Complexity429
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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