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ZDLD13

CAT: 0931-T60689-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60689-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2762278-95-3
Target
Others, Apoptosis, CDK
Related Pathways
Apoptosis, Others, Cell Cycle/Checkpoint
Bioactivity
ZDLD13 is a β-carboline that exhibits potent anti-HCT116 activity inclusive of inhibition of invasion and migration, inhibition of colony formation, inducing of apoptosis as well as arresting of G1 phase in cell cycle. ZDLD13 is an orally active and selective inhibitor of CDK4/CycD3 (IC 50 = 0.38 μM) which exhibits significant inhibition of tumor growth in HCT116 tumor xenograft model [1].
Smiles
C(NCC1=CC=CC=N1)(=O)C2=C3C(C=4C(N3)=CC=CC4)=CC=N2
Molecular Formula
C18H14N4O
Molecular Weight
302.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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