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TREM2 agonist-1

CAT: 0013-GTR19186099-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186099-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TREM2 agonist-1 (I-246) is a small molecule activator of the TREM2 receptor with reported EC50 values ranging from 3.0 to 100 μM. This compound is utilized in research to investigate TREM2's role in microglial function and neurodegenerative diseases, such as Alzheimer's, in both cellular and animal models. Due to stability concerns in its powder form, alternative salt formulations are recommended for experimental use.
CAS Number
2738486-70-7
Field of Research
Neuroscience; Pharmacology & Drug Discovery
Smiles
FC1=C (C=2C3=C (C=C (N2) [C@@H]4C[C@H] (OCC4) C5=CN (C) N=C5) N=C (C) C=N3) C=CC (Cl) =C1
Molecular Formula
C23H21ClFN5O
Molecular Weight
437.9
Storage Conditions
-20°C
Notes
For research use only.

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