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TREM2 agonist-5

CAT: 0013-GTR19264416-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19264416-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TREM2 agonist-5 is a ligand for the microglial lipid-sensing receptor (TREM2) and acts as an agonist with a Kd of 71.36 μM. It is the racemic analog of the TREM2 agonist VG-3927 and demonstrates excellent microglial phagocytic activity in HEK293-hTREM2/DAP12 cells, effectively activating TREM2 signaling. TREM2 agonist-5 has superior in vitro pharmacokinetics compared to VG-3927 and is potentially useful for Alzheimer's disease research.
Field of Research
Neuroscience; Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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