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TREM2-IN-1

CAT: 0013-GTR19235390Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235390Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TREM2-IN-1 (OPA) is a platinum-based small molecule that inhibits TREM2 on myeloid cells and exhibits anti-cancer activity by blocking DNA replication. It has been shown in a mouse colorectal cancer model to suppress immune regulatory activity, reducing markers like CD206 and CX3CR1, supporting its use in oncology and immunology research.
CAS Number
2000236-36-0
Field of Research
Cell Biology, Neuroscience
Purity
98.56% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (2.83 mM) ; DMSO:80 mg/mL (68.72 mM)
Smiles
[O-] (C (CCC (O[C@@H]1O[C@]2 ([C@]34[C@] ([C@H]1C) (CC[C@@H] (C) [C@@]3 (CC[C@] (C) (O2) OO4) [H]) [H]) [H]) =O) =O) [Pt+4]56 ([O-]C (CCC (O[C@@H]7O[C@]8 ([C@]9%10[C@] ([C@H]7C) (CC[C@@H] (C) [C@@]9 (CC[C@] (C) (O8) OO%10) [H]) [H]) [H]) =O) =O) ([NH2]C%11C ([NH2]5) CCCC%11) [O-]C (=O) C (=O) [O-]6
Molecular Formula
C46H68N2O20Pt
Molecular Weight
1164.12
Storage Conditions
-20°C
Notes
For research use only.

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