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CJ-2360

CAT: 0013-GTR19185658-02Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185658-02Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CJ-2360 is a potent, orally bioavailable ALK inhibitor effective against wild-type and multiple resistant mutants, including L1196M and C1156Y. Its broad kinase profile also includes LTK and MERTK, supporting its utility in preclinical in vitro and in vivo studies of ALK-driven oncology research.
CAS Number
2226742-61-4
Field of Research
Cardiovascular Research, Signal Transduction
Smiles
O=C1C2=C (N (C (C) C) C=3C1=CC (OC) =C (C3F) N4C[C@H] (C) N (C) [C@H] (C) C4) NC=5C2=CC=C (C#N) C5
Molecular Formula
C27H30FN5O2
Molecular Weight
475.56
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

CID 134524157
CAS Number2226742-61-4
PubChem CID134524157
IUPAC Name4-fluoro-2-methoxy-11-oxo-5-propan-2-yl-3-[(3R,5S)-3,4,5-trimethylpiperazin-1-yl]-6H-indolo[2,3-b]quinoline-8-carbonitrile
Molecular FormulaC27H30FN5O2
Molecular Weight475.6
XLogP5
Topological Polar Surface Area75.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Heavy Atom Count35
Formal Charge0
Complexity850
SMILES
C[C@@H]1CN(C[C@@H](N1C)C)C2=C(C=C3C(=C2F)N(C4=C(C3=O)C5=C(N4)C=C(C=C5)C#N)C(C)C)OC
InChI
InChI=1S/C27H30FN5O2/c1-14(2)33-24-19(26(34)22-18-8-7-17(11-29)9-20(18)30-27(22)33)10-21(35-6)25(23(24)28)32-12-15(3)31(5)16(4)13-32/h7-10,14-16,30H,12-13H2,1-6H3/t15-,16+
InChIKey
LOONVQWRKJLEEG-IYBDPMFKSA-N
Chemical Structure
2D Structure
2D structure of CID 134524157
CAS: 2226742-61-4
CID: 134524157
Formula: C27H30FN5O2
MW: 475.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight475.6
XLogP35
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count3
Exact Mass475.23835338
Monoisotopic Mass475.23835338
Topological Polar Surface Area75.6 Ų
Heavy Atom Count35
Formal Charge0
Complexity850
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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