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FLT3/ITD-IN-2

CAT: 0013-GTR19185387-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185387-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FLT3/ITD-IN-2 is a highly potent and selective small molecule inhibitor of FLT3, FLT3-ITD, and the FLT3D835Y mutant, with IC50 values in the sub-nanomolar to low nanomolar range. It effectively blocks FLT3 phosphorylation and suppresses the proliferation of acute myeloid leukemia (AML) cells in vitro, making it a valuable chemical probe for oncology research targeting FLT3-driven leukemias.
CAS Number
2489446-59-3
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (NC1=C (C (F) (F) F) C=C (C=C1) N2CCOCC2) (=O) C3=C4N (N=C3) C=CC (N[C@@H]5CCCNC5) =N4
Molecular Formula
C23H26F3N7O2
Molecular Weight
489.49
Storage Conditions
-20°C
Notes
For research use only.

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