BCR-ABL-IN-4

CAT: 0013-GTR19184678-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19184678-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

BCR-ABL-IN-4 is a potent small molecule inhibitor targeting BCR-ABL, demonstrating significant anti-proliferative activity in vitro. It effectively inhibits K562 cells (IC50: 0.67 nM) and the resistant BCR-ABL T315I mutant in Ba/F3 cells (IC50: 16 nM), making it a valuable tool for chronic myeloid leukemia (CML) and drug resistance research.

CAS Number

2669790-59-2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

C (NC1=CC=C (OC (Cl) (F) F) C=C1) (=O) C2=CC (=C (N=C2) N3C[C@H] (O) CC3) C=4C=C5C (=NC4) CN (C5=O) C6CC6

Molecular Formula

C27H24ClF2N5O4

Molecular Weight

555.96

Storage Conditions

-20°C

Notes

For research use only.

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BCR-ABL-IN-4

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