BCR-ABL-IN-5

CAT: 0013-GTR19185329-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19185329-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

BCR-ABL-IN-5 is a potent inhibitor of both wild-type and T315I mutant Bcr-Abl kinase, with respective IC50 values of 0.014 μM and 0.45 μM. It demonstrates anti-proliferative activity in leukemic cell studies and serves as a valuable research tool for investigating chronic myeloid leukemia (CML) resistance mechanisms in vitro.

CAS Number

1795736-60-5

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Smiles

NC=1C2=C (C=CC=C2NN1) C3=CC=C (C (=O) N4CCN (C (=O) C5=C (Cl) C=C (Cl) C=C5) CC4) C=C3

Molecular Formula

C25H21Cl2N5O2

Molecular Weight

494.37

Storage Conditions

-20°C

Notes

For research use only.

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BCR-ABL-IN-5

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