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EGFR-IN-49

CAT: 0013-GTR19186503-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186503-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-49 is a selective small molecule inhibitor targeting EGFR T790M and T790M/L858R mutants with IC50 values of 65.0 nM and 13.6 nM, respectively. It induces dose-dependent apoptosis and is a useful tool compound for in vitro and in vivo studies of non-small cell lung cancer resistance mechanisms.
CAS Number
2459932-81-9
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
O (C1=C2C (=NC (NC3=CC (C#N) =CC=C3) =N1) C=CS2) C4=CC (NC (C=C) =O) =CC=C4
Molecular Formula
C22H15N5O2S
Molecular Weight
413.45
Storage Conditions
-20°C
Notes
For research use only.

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