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PARP1-IN-49

CAT: 0013-GTR19273712-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273712-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PARP1-IN-49 is a selective inhibitor of PARP1 with an IC50 value of 23.56 nM and a Kd of 17.78 nM. It exhibits higher selectivity for PARP1 over PARP2. By inhibiting PARP1, PARP1-IN-49 induces DNA damage, cell cycle arrest, and apoptosis (apoptosis) . Additionally, it increases intracellular reactive oxygen species (ROS) levels and inhibits cell migration. This compound is applicable in breast and ovarian cancer research.
Storage Conditions
-20°C
Notes
For research use only.

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