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JAK-IN-20

CAT: 0013-GTR19185060-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19185060-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK-IN-20 is a potent, orally bioavailable pan-JAK inhibitor targeting JAK1, JAK2, and JAK3 with IC50 values of 7, 5, and 14 nM, respectively. It exhibits excellent pharmacokinetics and anti-inflammatory activity in vivo, making it suitable for research in autoimmune diseases, inflammation models, and hematological malignancies as per published studies.
CAS Number
1654776-91-6
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Smiles
FC=1C (=NC (NC2=CC=C (C=C2) N3CCC (CC3) N4CCOCC4) =NC1) C5=CC=C (C (NCC#N) =O) C=C5
Molecular Formula
C28H30FN7O2
Molecular Weight
515.58
Storage Conditions
-20°C
Notes
For research use only.

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