JAK-IN-39

CAT: 0013-GTR19250302-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19250302-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

JAK-IN-39 (compound 11) is a potent and selective pan-JAK inhibitor with sub-nanomolar IC50 values against JAK1, JAK2, and JAK3. It demonstrates functional activity by reducing TF-1 cell viability and suppressing pro-inflammatory cytokine production, such as TNFα and IFNγ, in lymphocyte assays, supporting its use in immunology and oncology research.

CAS Number

2250013-34-2

Field of Research

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology

Smiles

N (C=1N2C (=CC (=N2) C=3N=C (OC) C=CC3) N=CC1C (N) =O) [C@H]4C (C) (C) CN (CC4) C5=CC=C (C#N) N=N5

Molecular Formula

C25H26N10O2

Molecular Weight

498.54

Storage Conditions

-20°C

Notes

For research use only.

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