Liothyronine (GMP)
CAT:
804-HY-A0070AG-02
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Liothyronine (GMP)
- CAS Number: 6893-02-3
- UNSPSC Description: Liothyronine (Triiodothyronine) (GMP) is the Liothyronine (HY-A0070A) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively[1].
- Target Antigen: Thyroid Hormone Receptor
- Type: GMP Small Molecules
- Related Pathways: Vitamin D Related/Nuclear Receptor
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cancer; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/liothyronine-gmp.html
- Solubility: 10 mM in DMSO
- Smiles: OC1=C(I)C=C(OC2=C(I)C=C(C[C@H](N)C(O)=O)C=C2I)C=C1
- Molecular Weight: 650.97
- References & Citations: [1]Aasen T, et al. Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells. Nat Protoc. 2010 Feb;5(2):371-82. |[2]Yu M, et al. An important role for adenine, cholera toxin, hydrocortisone and triiodothyronine in the proliferation, self-renewal and differentiation of limbal stem cells in vitro. Exp Eye Res. 2016 Nov;152:113-122. |[3]CY, et al. Triiodothyronine promotes cardiac differentiation and maturation of embryonic stem cells via the classical genomic pathway. Mol Endocrinol. 2010 Sep;24(9):1728-36. |[4]Wang L, et al. Triiodothyronine and dexamethasone alter potassium channel expression and promote electrophysiological maturation of human-induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2021 Dec;161:130-138.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported