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Liothyronine

CAT: 0931-T1653-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T1653-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
6893-02-3
Target
Endogenous Metabolite, Thyroid hormone receptor (THR)
Related Pathways
Endocrinology/Hormones, Metabolism
Purity
0.9933
Bioactivity
Liothyronine (Tresitope) is a synthetic and highly active thyroid hormone that acts as an effective agonist of TRα and TRβ (Ki = 2.33 nM for both hTRα and hTRβ) . It activates the TRβ1 receptor, promotes the metabolism of carbohydrates, proteins, and fats, accelerates the oxidative processes in tissue cells, maintains basal metabolic rate, and supports normal growth and development. Liothyronine can be used to induce hyperthyroidism models.
Smiles
N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O
Molecular Formula
C15H12I3NO4
Molecular Weight
650.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C