Products for Research Use Only
RegisterLogin

Methyldopa

CAT: 0013-GTR19176996-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19176996-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Methyldopa (MK-351) is a psychoactive antihypertensive agent that acts as a selective α2-adrenergic receptor agonist. It is widely used in cardiovascular research to study central sympathetic nervous system modulation in both in vivo models of hypertension and in vitro receptor binding assays.
CAS Number
555-30-6
Product Name Alternative
Prodrug, response, inhibit, L- (-) -α-Methyldopa, L-α-Methyldopa, metabolized, Methyldopa, MK351, MK-351, MK 351, Inhibitor, hyperglycemic, L-alpha-Methyldopa, L-a-Methyldopa, Dopamine Receptor, DopamineReceptor, DOPA decarboxylase, Beta Receptor, AdrenergicReceptor, Adrenergic Receptor, antihyoertensive
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
98.95% (May vary between batches)
Solubility
DMSO:60 mg/mL (284.08 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.47 mM)
Smiles
C ([C@] (C (O) =O) (C) N) C1=CC (O) =C (O) C=C1
Molecular Formula
C10H13NO4
Molecular Weight
211.21
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Methyldopa

Alpha-methyl-L-dopa is a derivative of L-tyrosine having a methyl group at the alpha-position and an additional hydroxy group at the 3-position on the phenyl ring. It has a role as an alpha-adrenergic agonist, an antihypertensive agent, a peripheral nervous system drug, a hapten and a sympatholytic agent. It is a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid.

CAS Number555-30-6
PubChem CID38853
IUPAC Name(2S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
Molecular FormulaC10H13NO4
Molecular Weight211.21
XLogP-1.9
Topological Polar Surface Area104
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count15
Formal Charge0
Complexity246
SMILES
C[C@](CC1=CC(=C(C=C1)O)O)(C(=O)O)N
InChI
InChI=1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1
InChIKey
CJCSPKMFHVPWAR-JTQLQIEISA-N
Chemical Structure
2D Structure
2D structure of Methyldopa
CAS: 555-30-6
CID: 38853
Formula: C10H13NO4
MW: 211.21
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight211.21
XLogP3-1.9
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass211.08445790
Monoisotopic Mass211.08445790
Topological Polar Surface Area104 Ų
Heavy Atom Count15
Formal Charge0
Complexity246
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19191979-01Methyldopate
GTR19202447-01Methyldopate hydrochloride

Alternative Products

CatalogName
525617Methyldopa
HY-121809DL-Methyldopa
T69105-01Methyldopa anhydrous
M15017-01L- (-) -α-Methyldopa
CS-O-60086Methyldopa-d3
TYD-04592-01Methyldopa-CoA
MBS5774792-01alpha-Methyldopa
BUP18450Methyldopa hydrate
HY-B0225AMethyldopa (hydrochloride)
453098-01L- (-) -a-Methyldopa

Popular Products