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Mitotane

CAT: 0013-GTR19176671-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19176671-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mitotane is an adrenocorticolytic agent derived from DDD, selectively targeting and inhibiting adrenal cortical cells and hormone production. It is used in research models of adrenocortical carcinoma and Cushing's syndrome, with studies demonstrating its cytotoxic effects in both in vitro and in vivo experimental settings.
CAS Number
53-19-0
Product Name Alternative
Mitotan, Mitotane, o, p'-DDD, NCI-C04933, NCI-C-04933, NCI-C 04933, Inhibitor, inhibit, H295R, HepaRG, cholesterol, drug-drug interactions, corticotroph cells, antineoplastic, Apoptosis, 2,4′-DDD, adrenocortical carcinoma, Adrenodoxin, TαT1
Field of Research
Cell Biology, Neuroscience, Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:60 mg/mL (187.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.25 mM) ; Ethanol:60 mg/mL (187.48 mM)
Smiles
ClC (Cl) C (c1ccc (Cl) cc1) c1ccccc1Cl
Molecular Formula
C14H10Cl4
Molecular Weight
320.04
Storage Conditions
-20°C
Notes
For research use only.

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