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HBF-0259

CAT: 0013-GTR19174641-04Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174641-04Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HBF-0259 is a small molecule inhibitor of hepatitis B virus surface antigen (HBsAg) secretion, demonstrating potent antiviral activity with EC50 values in the low micromolar range and a favorable cytotoxicity profile in cellular models. This compound is a valuable research tool for investigating HBV replication and exploring novel therapeutic strategies in virology and infectious disease research.
CAS Number
957011-15-3
Product Name Alternative
Antiviral, antigen, Inhibitor, HBF 0259, HBF0259, HBF-0259, Hepatitis B virus, hepatitis, HBV, HBsAg, inhibit, surface, secretion, virus
Field of Research
Immunology & Inflammation, Infectious Disease & Virology
Purity
90.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (9.06 mM) ; DMSO:98 mg/mL (269.08 mM)
Smiles
Fc1cccc (Cl) c1C1CC (N=C2N=NNN12) c1ccc (Cl) cc1
Molecular Formula
C16H12Cl2FN5
Molecular Weight
364.2
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Hbf-0259

inhibits hepatitis B virus surface antigen secretion; structure in first source

CAS Number957011-15-3
PubChem CID4165150
IUPAC Name7-(2-chloro-6-fluorophenyl)-5-(4-chlorophenyl)-4,5,6,7-tetrahydrotetrazolo[1,5-a]pyrimidine
Molecular FormulaC16H12Cl2FN5
Molecular Weight364.2
XLogP4.5
Topological Polar Surface Area55.6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count24
Formal Charge0
Complexity437
SMILES
C1C(NC2=NN=NN2C1C3=C(C=CC=C3Cl)F)C4=CC=C(C=C4)Cl
InChI
InChI=1S/C16H12Cl2FN5/c17-10-6-4-9(5-7-10)13-8-14(24-16(20-13)21-22-23-24)15-11(18)2-1-3-12(15)19/h1-7,13-14H,8H2,(H,20,21,23)
InChIKey
BRBZPYDLUUWBCD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Hbf-0259
CAS: 957011-15-3
CID: 4165150
Formula: C16H12Cl2FN5
MW: 364.2
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight364.2
XLogP34.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass363.0453790
Monoisotopic Mass363.0453790
Topological Polar Surface Area55.6 Ų
Heavy Atom Count24
Formal Charge0
Complexity437
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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