Products for Research Use Only
RegisterLogin

BI-0252

CAT: 0013-GTR19203940-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203940-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BI-0252 is a potent and selective MDM2-p53 interaction inhibitor with an IC50 of 4 nM. It demonstrates robust in vivo efficacy, inducing complete tumor regression in SJSA-1 xenograft models, which is associated with activation of p53 target genes and apoptotic markers. This molecule is a valuable chemical probe for researching p53 pathway biology in cancer models both in vitro and in vivo.
CAS Number
1818291-27-8
Field of Research
Cell Biology, Protein Biochemistry
Smiles
C (N1[C@@]2 ([C@H] ([C@]3 ([C@@]1 (C[C@@H] (N3) C4=CC=C (C (O) =O) C=C4) [H]) [H]) C5=C (F) C (Cl) =CC=C5) C=6C (NC2=O) =CC (Cl) =CC6) C7CC7
Molecular Formula
C30H26Cl2FN3O3
Molecular Weight
566.45
Storage Conditions
-20°C
Notes
For research use only.

Related Products

CatalogName
GTR19203938-01BI-167107
GTR19203937-01BI-1950
GTR19203933-01BI-4924
GTR19203919-01BI 689648
GTR19181986Bi-linderone
GTR19233355-01BI-4732
GTR19339331-01DFHBI-BI
GTR19173795-01BI-69A11
GTR19171677-01BI-D1870
GTR19169695-01BI-4464

Alternative Products

CatalogName
MBS3845265-01BI-0252
A20824-25BI-0252 25mg
A20824-10BI-0252 10mg
A20824-50BI-0252 50mg
A20824-5BI-0252 5mg
A20824-100BI-0252 100mg
A20824-1BI-0252 1mg
B2798-500BI
S0099Scavenger Receptor BI (SR-BI)
MBS131573BI-9564 (BI 9564; BI9564)

Popular Products