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Mutated EGFR-IN-1

CAT: 0013-GTR19175423-01Size: 1 ml x 10 mM (in DMSO)Dry Ice: NoHazardous: No
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CAT#:0013-GTR19175423-01Size:1 ml x 10 mM (in DMSO)
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mutated EGFR-IN-1, an analog of Osimertinib, serves as a key chemical intermediate for developing inhibitors targeting oncogenic EGFR mutants including L858R, exon 19 deletions, and the resistant T790M variant. It is utilized in preclinical research for both in vitro enzymatic assays and in vivo efficacy studies in relevant xenograft models.
CAS Number
1421372-66-8
Product Name Alternative
Mutated EGFRIN1, Mutated EGFR-IN-1, Mutated EGFR IN 1, inhibit, Osimertinib, Osimertinib analog, EGFR, EGFR (L858R), EGFR (T790M), EGFR (Exon 19 deletion/T790M), EGFRT790M, EGFRExon 19 deletion/T790M, EGFRL858R, Epidermal growth factor receptor, ErbB-1, Inhibitor, HER1
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Purity
98.91% (May vary between batches)
Solubility
DMSO:7.5 mg/mL (16.83 mM)
Smiles
COc1cc (N (C) CCN (C) C) c (N) cc1Nc1nccc (n1) -c1cn (C) c2ccccc12
Molecular Formula
C25H31N7O
Molecular Weight
445.56
Storage Conditions
-20°C
Notes
For research use only.

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