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PF-915275

CAT: 0013-GTR19174526-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174526-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PF-915275 is a potent and selective inhibitor of human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1), exhibiting a Ki of 2.3 nM. It effectively blocks the conversion of cortisone to cortisol in vitro, with EC50 values of 20 nM in human hepatocytes and 100 nM in monkey hepatocytes, supporting metabolic disease research.
CAS Number
857290-04-1
Product Name Alternative
PF 915275, PF915275, PF-915275, inhibit, Inhibitor, 11βHSD1, 11β-HSD1
Field of Research
Metabolism Research
Purity
97.69% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.85 mM) ; DMSO:60 mg/mL (171.24 mM)
Smiles
Nc1cccc (NS (=O) (=O) c2ccc (cc2) -c2ccc (cc2) C#N) n1
Molecular Formula
C18H14N4O2S
Molecular Weight
350.39
Storage Conditions
-20°C
Notes
For research use only.

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Alternative Products

CatalogName
T16510-01PF-915275
3291/10PF 915275
A21330-5PF-915275 5mg
A21330-2PF-915275 2mg
A21330-500PF-915275 500mg
A21330-25PF-915275 25mg
HY-18056R-01PF-915275 (Standard)
A21330-100PF-915275 100mg
A21330-50PF-915275 50mg
A21330-10PF-915275 10mg

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