Products for Research Use Only

Mal-PEG1-NHS ester

CAT: 0013-GTR19174291-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174291-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Mal-PEG1-NHS ester is a cleavable, polyethylene glycol-based bifunctional linker employed in constructing both antibody-drug conjugates (ADCs) and proteolysis-targeting chimeras (PROTACs) . Its application facilitates targeted drug delivery and protein degradation studies in biochemical and cell-based research, supporting investigations into novel therapeutic strategies.
CAS Number
1807518-72-4
Product Name Alternative
PEG, PROTAC, PROTAC Linker, PROTAC Linkers, PROTACLinker, Linker, inhibit, Inhibitor, MalPEG1NHS ester, Mal-PEG-1-NHS ester, Mal-PEG1-NHS ester, Mal PEG1 NHS ester, Cleavable, ADC Linker, ADCLinker, ADC Linkers, ADC, Antibody-drug conjugates linkers
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Purity
98.19% (May vary between batches)
Smiles
O=C (CCOCCN1C (=O) C=CC1=O) ON1C (=O) CCC1=O
Molecular Formula
C13H14N2O7
Molecular Weight
310.26
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Mal-PEG1-NHS ester
CAS Number1807518-72-4
PubChem CID59992617
IUPAC Name(2,5-dioxopyrrolidin-1-yl) 3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoate
Molecular FormulaC13H14N2O7
Molecular Weight310.26
XLogP-1.7
Topological Polar Surface Area110
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Heavy Atom Count22
Formal Charge0
Complexity521
SMILES
C1CC(=O)N(C1=O)OC(=O)CCOCCN2C(=O)C=CC2=O
InChI
InChI=1S/C13H14N2O7/c16-9-1-2-10(17)14(9)6-8-21-7-5-13(20)22-15-11(18)3-4-12(15)19/h1-2H,3-8H2
InChIKey
AMRJPIJPLBUEHO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Mal-PEG1-NHS ester
CAS: 1807518-72-4
CID: 59992617
Formula: C13H14N2O7
MW: 310.26
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight310.26
XLogP3-1.7
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count7
Rotatable Bond Count8
Exact Mass310.08010079
Monoisotopic Mass310.08010079
Topological Polar Surface Area110 Ų
Heavy Atom Count22
Formal Charge0
Complexity521
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes