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PX-12

CAT: 0013-GTR19174038-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19174038-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PX-12 is a thioredoxin-1 (Trx-1) inhibitor that induces apoptosis and suppresses HIF-1α and VEGF, demonstrating antitumor activity in preclinical models. It is a research tool for studying cancer mechanisms and has been evaluated in clinical trials for advanced metastatic cancers.
CAS Number
141400-58-0
Product Name Alternative
Inhibit, IV 2, IV2, IV-2, PX12, PX-12, PX 12, Inhibitor, TRX (HT-29 cells), TRX (MCF-7)
Field of Research
Cell Biology, Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:38 mg/mL (201.79 mM) ; DMSO:48 mg/mL (254.9 mM)
Smiles
CCC (C) SSc1ncc[nH]1
Molecular Formula
C7H12N2S2
Molecular Weight
188.31
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Px-12

2-(butan-2-yldisulfanyl)-1H-imidazole is a member of imidazoles.

CAS Number141400-58-0
PubChem CID219104
IUPAC Name2-(butan-2-yldisulfanyl)-1H-imidazole
Molecular FormulaC7H12N2S2
Molecular Weight188.3
XLogP2.3
Topological Polar Surface Area79.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Heavy Atom Count11
Formal Charge0
Complexity111
SMILES
CCC(C)SSC1=NC=CN1
InChI
InChI=1S/C7H12N2S2/c1-3-6(2)10-11-7-8-4-5-9-7/h4-6H,3H2,1-2H3,(H,8,9)
InChIKey
BPBPYQWMFCTCNG-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Px-12
CAS: 141400-58-0
CID: 219104
Formula: C7H12N2S2
MW: 188.3
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight188.3
XLogP32.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass188.04419074
Monoisotopic Mass188.04419074
Topological Polar Surface Area79.3 Ų
Heavy Atom Count11
Formal Charge0
Complexity111
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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CatalogName
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sc-358518PX 12

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