Products for Research Use Only

ML-090

CAT: 0013-GTR19173992Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19173992Size:5 mg
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Description
ML-090 is a potent and selective small molecule inhibitor of NADPH oxidase 1 (NOX1), exhibiting an IC50 of 90 nM. It demonstrates >100-fold selectivity over NOX2, NOX3, and NOX4 isoforms (IC50 >10 μM) . This inhibitor is a valuable research tool for studying NOX1's role in cellular redox signaling, inflammation, and cancer progression in both in vitro and in vivo models.
CAS Number
531-46-4
Product Name Alternative
ML090, ML-090, ML 090, NADPHoxidase, NADPH Oxidase, NOX, NOX1, NOX2, NOX3, NOX4, inhibit, Inhibitor, Fluoflavine, HEK293 cell
Field of Research
Immunology & Inflammation, Metabolism Research
Purity
98.23% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
N1c2ccccc2Nc2nc3ccccc3nc12
Molecular Formula
C14H10N4
Molecular Weight
234.26
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

6,11-Dihydroquinoxalino[2,3-b]quinoxaline

6,11-dihydroquinoxalino[2,3-b]quinoxaline is a quinoxaline derivative.

CAS Number531-46-4
PubChem CID616479
IUPAC Name6,11-dihydroquinoxalino[2,3-b]quinoxaline
Molecular FormulaC14H10N4
Molecular Weight234.26
XLogP2.7
Topological Polar Surface Area49.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Heavy Atom Count18
Formal Charge0
Complexity278
SMILES
C1=CC=C2C(=C1)NC3=NC4=CC=CC=C4N=C3N2
InChI
InChI=1S/C14H10N4/c1-2-6-10-9(5-1)15-13-14(16-10)18-12-8-4-3-7-11(12)17-13/h1-8H,(H,15,17)(H,16,18)
InChIKey
WGKYYZDYHYOKQV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 6,11-Dihydroquinoxalino[2,3-b]quinoxaline
CAS: 531-46-4
CID: 616479
Formula: C14H10N4
MW: 234.26
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight234.26
XLogP32.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count0
Exact Mass234.090546336
Monoisotopic Mass234.090546336
Topological Polar Surface Area49.8 Ų
Heavy Atom Count18
Formal Charge0
Complexity278
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes