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ML-T7

CAT: 0013-GTR19234962-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19234962-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML-T7 is a potent Tim-3 inhibitor that blocks interactions with PtdSer and CEACAM1. It enhances the antitumor function of CTLs, CAR T cells, and NK cells in vitro and improves dendritic cell antigen presentation. This compound demonstrates efficacy in preclinical tumor models, supporting its investigation as a monotherapy or combined with checkpoint inhibitors like Nivolumab.
CAS Number
459789-75-4
Field of Research
Immunology & Inflammation
Smiles
O=C1C2 (C3C (C (O2) C4=CC=C (C) C=C4) C (=O) N (C3=O) C5=C (Cl) C=C (Cl) C=C5) C (=O) C=6C1=CC=CC6
Molecular Formula
C27H17Cl2NO5
Molecular Weight
506.33
Storage Conditions
-20°C
Notes
For research use only.

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