c-Myb Oncoprotein

c-Myb Oncoprotein

• Gene Name: [MYB]
• NCBI Gene ID: 4602
• Reactivity: Human.
• Storage Conditions: Store at 2 to 8 °C. Antibody is stable for 24 months.
• Specificity: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular hom- olog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-ter- minal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
• Other Gene Names: [MYB; MYB; efg; Cmyb; c-myb; c-myb_CDS]
• Short Name: [c-Myb Oncoprotein]
• Other Product Names: [transcriptional activator Myb isoform 3; Transcriptional activator Myb; transcriptional activator Myb; c-myb8B_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; proto-oncogene c-Myb; c-myb protein (140 AA); v-myb avian myeloblastosis viral oncogene homolog; Proto-oncogene c-Myb]
• NCBI GI Number: 194328727
• NCBI Accession Number: NP_001123644.1
• NCBI GB Accession Number: NM_001130172.1
• Uniprot Accession Number: P10242