c-Myb Oncoprotein

• Gene Name:

  [MYB]

• NCBI Gene ID:

  4602

• Reactivity:

  Human.

• Storage Conditions:

  Store at 2 to 8 °C. Antibody is stable for 24 months.

• Specificity:

  The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular hom- olog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-ter- minal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

• Other Gene Names:

  [MYB; MYB; efg; Cmyb; c-myb; c-myb_CDS]

• Short Name:

  [c-Myb Oncoprotein]

• Other Product Names:

  [transcriptional activator Myb isoform 3; Transcriptional activator Myb; transcriptional activator Myb; c-myb8B_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; proto-oncogene c-Myb; c-myb protein (140 AA); v-myb avian myeloblastosis viral oncogene homolog; Proto-oncogene c-Myb]

• NCBI GI Number:

  194328727

• NCBI Accession Number:

  NP_001123644.1

• NCBI GB Accession Number:

  NM_001130172.1

• Uniprot Accession Number:

  P10242