c-Myb Antibody / MYB

c-Myb Antibody / MYB

• Description: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
• CAS Number: 9007-83-4
• UniProt: P01104
• Host: Mouse
• Immunogen: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.
• Clonality: Monoclonal
• Isotype: IgG1 κ
• Applications: ELISA
• Format: Purified
• Buffer: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
• Reconstitution: Store the c-Myb antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
• Limitations: This c-Myb antibody is available for research use only.