RO 46-8443

CAT: 0013-GTR19172258-01Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19172258-01Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

RO 46-8443 is a selective, non-peptide antagonist of the endothelin ETB receptor, exhibiting up to 2000-fold selectivity in both binding and functional assays. This tool compound is used in vitro and in vivo to investigate ETB receptor function in cardiovascular and renal research.

CAS Number

175556-12-4

Product Name Alternative

Hypertensive rats, ET-B, ETB, EndothelinReceptor, Endothelin Receptor, Inhibitor, normotensive, non-peptide, inhibit, RO 46 8443, RO 468443, Ro 46-8443, RO 46-8443, selective

Field of Research

Pharmacology & Drug Discovery

Purity

98.50% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.28 mM) ; DMSO:55 mg/mL (90.21 mM)

Smiles

COc1ccc (cc1) -c1nc (NS (=O) (=O) c2ccc (cc2) C (C) (C) C) c (Oc2ccccc2OC) c (OC[C@H] (O) CO) n1

Molecular Formula

C31H35N3O8S

Molecular Weight

609.69

Storage Conditions

-20°C

Notes

For research use only.

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HY-19431-01	Ro 46-8443
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RO 46-8443

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