NS-638

CAT: 0013-GTR19172167-06Size: 50 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0013-GTR19172167-06Size:50 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

NS-638 is a calcium channel blocker that inhibits potassium-stimulated intracellular calcium elevation with an IC50 of 3.4 μM. This small molecule is a useful research tool for studying calcium signaling pathways in cardiovascular and neurological research, applicable in both in vitro and in vivo experimental models.

CAS Number

150493-34-8

Product Name Alternative

Ca channels, Ca2+ channels, Calcium Channel, CalciumChannel, NS638, NS-638, NS 638, Inhibitor, K+-stimulated intracellular Ca2+-elevation, inhibit

Field of Research

Metabolism Research, Pharmacology & Drug Discovery

Purity

98.44% (May vary between batches)

Solubility

DMSO:55 mg/mL (168.86 mM)

Smiles

Nc1nc2cc (ccc2n1Cc1ccc (Cl) cc1) C (F) (F) F

Molecular Formula

C15H11ClF3N3

Molecular Weight

325.72

Storage Conditions

-20°C

Notes

For research use only.

Chemical Information

2-Amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole

structure given in first source

CAS Number	150493-34-8
PubChem CID	127722
IUPAC Name	1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)benzimidazol-2-amine
Molecular Formula	C15H11ClF3N3
Molecular Weight	325.71
XLogP	4.2
Topological Polar Surface Area	43.8
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Heavy Atom Count	22
Formal Charge	0
Complexity	385

SMILES

C1=CC(=CC=C1CN2C3=C(C=C(C=C3)C(F)(F)F)N=C2N)Cl

InChI

InChI=1S/C15H11ClF3N3/c16-11-4-1-9(2-5-11)8-22-13-6-3-10(15(17,18)19)7-12(13)21-14(22)20/h1-7H,8H2,(H2,20,21)

InChIKey

GXQCVUZORDAARJ-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 150493-34-8

CID: 127722

Formula: C15H11ClF3N3

MW: 325.71

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	325.71
XLogP3	4.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	2
Exact Mass	325.0593595
Monoisotopic Mass	325.0593595
Topological Polar Surface Area	43.8 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	385
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
GTR19210647-01	BGC-638
GTR19203252-01	PKF050-638
GTR19276413-01	CRBN ligand-638
GTR18084448	Anti-Clathrin (619-638)
GTR18026447	NS Antibody
GTR18025589	NS Antibody
GTR19240332-01	NS-062
GTR19210470-01	NS-3736
GTR19196918-01	NS-220
GTR19196917-01	NS-2710

Alternative Products

Catalog	Name
M12097-01	NS-638
MBS579666	NS 638
A20460-50	NS-638 50mg
A20460-10	NS-638 10mg
A20460-5	NS-638 5mg
A20460-100	NS-638 100mg
A20460-25	NS-638 25mg
A20460-2	NS-638 2mg
A20460-10mM-D	NS-638 10mM * 1mL in DMSO
HY-114597-01	PKF050-638

NS-638

Chemical Information

Related Products

Alternative Products

Popular Products