NS-062

CAT: 0013-GTR19240332-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19240332-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

NS-062 is an irreversible covalent EGFR inhibitor with potent activity against resistant mutations. It demonstrates in vitro antiproliferative efficacy in H1975 cells (IC50 = 0.19 μM) and has shown in vivo antitumor activity in a murine H1975 xenograft model, supporting its use in oncology research for studying EGFR-driven resistance.

CAS Number

2226257-92-5

Field of Research

Cardiovascular Research, Infectious Disease & Virology, Signal Transduction

Smiles

N (C=1C2=C (C=C (OCCCN3CCOCC3) C (NC (=O) [C@@H]4N (C (C (Cl) F) =O) CCC4) =C2) N=CN1) C5=CC (Cl) =C (F) C=C5

Molecular Formula

C28H30Cl2F2N6O4

Molecular Weight

623.48

Storage Conditions

-20°C

Notes

For research use only.

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