PKF050-638

CAT: 0013-GTR19203252-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19203252-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

PKF050-638 is a potent and selective small molecule inhibitor of HIV-1 Rev function, exhibiting an IC50 of 0.04 μM. It acts by disrupting the CRM1-NES interaction, thereby blocking the CRM1-mediated nuclear export of Rev. This compound is a valuable research tool for studying HIV-1 replication and nucleocytoplasmic transport mechanisms in vitro.

CAS Number

528893-52-9

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Smiles

C (=C\C (OCC) =O) \N1C (=NC=N1) C2=C (N) C=CC (Cl) =C2

Molecular Formula

C13H13ClN4O2

Molecular Weight

292.72

Storage Conditions

-20°C

Notes

For research use only.

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PKF050-638

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