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BMS-345541

CAT: 0013-GTR19171953-02Size: 2 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171953-02Size:2 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-345541 (IKK Inhibitor III) is a selective small molecule inhibitor targeting IKK-2 and IKK-1 catalytic subunits with IC50 values of 0.3 μM and 4 μM, respectively. It is widely used in vitro and in vivo to study NF-κB signaling in inflammation, cancer, and immune response research.
CAS Number
445430-58-0
Product Name Alternative
BMS345541, BMS-345541, BMS-345541 free base, BMS 345541, IκB kinase, IκB, I kappa B kinase, IKK2, IkB/IKK, IkB, IKK Inhibitor III, IKK1, IKK
Field of Research
Signal Transduction
Purity
98.74% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.92 mM) ; DMSO:5.1 mg/mL (19.97 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1cnc2c (NCCN) nc3ccc (C) cc3n12
Molecular Formula
C14H17N5
Molecular Weight
255.32
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4(2'-Aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline

N'-(1,8-dimethyl-4-imidazo[1,2-a]quinoxalinyl)ethane-1,2-diamine is a quinoxaline derivative.

CAS Number445430-58-0
PubChem CID9813758
IUPAC NameN'-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)ethane-1,2-diamine
Molecular FormulaC14H17N5
Molecular Weight255.32
XLogP2.3
Topological Polar Surface Area68.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count19
Formal Charge0
Complexity310
SMILES
CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN
InChI
InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)
InChIKey
PSPFQEBFYXJZEV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4(2'-Aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline
CAS: 445430-58-0
CID: 9813758
Formula: C14H17N5
MW: 255.32
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight255.32
XLogP32.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass255.14839556
Monoisotopic Mass255.14839556
Topological Polar Surface Area68.2 Ų
Heavy Atom Count19
Formal Charge0
Complexity310
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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