Products for Research Use Only

BMS-986397

CAT: 0013-GTR19236195-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19236195-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BMS-986397 is a cereblon-based molecular glue degrader targeting casein kinase 1α (CK1α) . It induces rapid apoptosis and cell cycle arrest in TP53 wild-type acute myeloid leukemia (AML) cells, supporting its investigation in preclinical in vitro and in vivo models of AML.
CAS Number
2564486-44-6
Field of Research
Metabolism Research, Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Smiles
O=C1N (CC=2C1=CC=C (C (N[C@@H] ([C@@] (F) (F) F) C3=C (Cl) C=CC=N3) =O) C2) [C@@H]4C (=O) NC (=O) CC4
Molecular Formula
C21H16ClF3N4O4
Molecular Weight
480.82
Storage Conditions
-20°C
Notes
For research use only.

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