Products for Research Use Only
RegisterLogin

E-64

CAT: 0013-GTR19171805-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19171805-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
E-64
CAS Number
66701-25-5
Product Name Alternative
Proteinase inhibitor E 64, Proteinase inhibitor E64, Proteinase inhibitor E-64, inhibit, Inhibitor, Cathepsin, Autophagy, Bacterial, CysteineProtease, Cysteine protease, Cysteine Protease, E64, E-64, E 64
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Cysteine protease inhibitor
Form
Powder
Solubility
Soluble in a 1:1 mixture of Ethanol and water (up to 20 mg/ml)
Smiles
CC (C) CC (NC (=O) C1OC1C (O) =O) C (=O) NCCCCN=C (N) N
Molecular Formula
C15H27N5O5
Molecular Weight
357.41
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2S.3S) -trans-Epoxy succinyl-L-leucylamido- (4-guanidino) butane

Chemical Information

trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane

E64 is an epoxy monocarboxylic acid, a member of guanidines, a L-leucine derivative and a dicarboxylic acid monoamide. It has a role as an antiparasitic agent, a protease inhibitor and an antimalarial. It is a tautomer of an E64 zwitterion.

CAS Number66701-25-5
PubChem CID123985
IUPAC Name(2S,3S)-3-[[(2S)-1-[4-(diaminomethylideneamino)butylamino]-4-methyl-1-oxopentan-2-yl]carbamoyl]oxirane-2-carboxylic acid
Molecular FormulaC15H27N5O5
Molecular Weight357.41
XLogP-0.9
Topological Polar Surface Area172
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count11
Heavy Atom Count25
Formal Charge0
Complexity518
SMILES
CC(C)C[C@@H](C(=O)NCCCCN=C(N)N)NC(=O)[C@@H]1[C@H](O1)C(=O)O
InChI
InChI=1S/C15H27N5O5/c1-8(2)7-9(20-13(22)10-11(25-10)14(23)24)12(21)18-5-3-4-6-19-15(16)17/h8-11H,3-7H2,1-2H3,(H,18,21)(H,20,22)(H,23,24)(H4,16,17,19)/t9-,10-,11-/m0/s1
InChIKey
LTLYEAJONXGNFG-DCAQKATOSA-N
Chemical Structure
2D Structure
2D structure of trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)butane
CAS: 66701-25-5
CID: 123985
Formula: C15H27N5O5
MW: 357.41
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight357.41
XLogP3-0.9
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count6
Rotatable Bond Count11
Exact Mass357.20121898
Monoisotopic Mass357.20121898
Topological Polar Surface Area172 Ų
Heavy Atom Count25
Formal Charge0
Complexity518
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19273004-01HDAC6-IN-64
GTR19240989-01NLRP3-IN-64
GTR19230362-01HDAC-IN-64
GTR19171383-01MN-64
GTR19160176-01MN-64
GTR19156699-01BOT-64
GTR19335078-01FM4-64
GTR19196976-01NB-64
GTR19187336-01EGFR-IN-64
GTR19235173-01HSD17B13-IN-64

Alternative Products

CatalogName
255209-01E 64
HY-15282-01E-64

Popular Products