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ISRIB

CAT: 0013-GTR19171665-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19171665-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ISRIB (trans-isomer) is a potent PERK inhibitor (IC50=5 nM) that reverses translational suppression and stress granule assembly induced by phosphorylated eIF2α. This small molecule is a valuable research tool for studying the integrated stress response in cellular and animal models of neurodegeneration and other diseases.
CAS Number
1597403-47-8
Product Name Alternative
Trans-ISRIB
Field of Research
Neuroscience, Protein Biochemistry
Purity
>98%
Bioactivity
Integrated stress response inhibitor
Form
Powder
Solubility
DMSO (up to 5 mg/ml with warming)
Smiles
Clc1ccc (OCC (=O) N[C@H]2CC[C@@H] (CC2) NC (=O) COc2ccc (Cl) cc2) cc1
Molecular Formula
C22H24Cl2N2O4
Molecular Weight
451.34
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N.N’-trans-1,4-Cyclohexanediylbis[2- (4-chlorophenoxy) acetamide

Alternative Products

CatalogName
C07266-1gISRIB
256959-01Trans-ISRIB

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